Great Ones. I think so. I think they're the same thing as the monsters who live in the cracks between worlds in Todash space.

They were a bit too much like sea creatures for my liking rather than the insectoid/centipede creatures described elsewhere. I guess there could be different kinds.

Anyhow. I bought both issues recently. Not bad at all although not much in the way of surprises.
Spoiler:
The artist's take on the Can-toi was eerie. The Taheen could have used a couple more weasel-heads, I think. I particularly liked Sheemie controlling the headless horse.